The global mRNA synthesis raw materials market size was estimated at USD 1.72 billion in 2023 and is anticipated to grow at a CAGR of 2.85% from 2024 to 2030. mRNA is synthesized by the process of transcription in the nucleus by using a template made up of a DNA nucleotide sequence. It includes various steps such as initiation, elongation, editing, and termination. mRNA synthesis has a broad range of applications in drug discovery, vaccine development, and the manufacturing of therapeutics. RNA-based vaccines have better immunogenicity, higher efficiency, and require short production time. The key factors driving the market growth include the growing academic and industrial interest in mRNA technology, the advantages of mRNA vaccines, and increasing funding for research.

The COVID-19 pandemic created new opportunities for mRNA technology platforms with the introduction and widespread use of vaccines. Government agencies from several nations, research institutions, and numerous biotech and pharmaceutical companies are focusing on efficient and quick methods for the rapid detection of COVID-19. mRNA vaccines are a safe and efficient method for preventing COVID-19. In addition, the advantages associated with the mRNA-based COVID-19 vaccines have sparked the attention of pharmaceutical businesses in delivering vaccines swiftly across the globe.

Gather more insights about the market drivers, restrains and growth of the Global mRNA synthesis raw materials market

mRNA Synthesis Raw Materials Market Segments Highlights:

• Based on type, the capping agents segment dominated the global industry with the largest revenue share of 39.17% in 2023. Capping and tailing are important steps in the production of active mRNA for use in functional studies. The segment is also anticipated to expand at the fastest CAGR of 3.26% during the forecast period.
• The vaccine production segment dominated the global industry with the largest revenue share in 2023. This can be attributed to the rapid production of mRNA vaccines compared to the conventional vaccines that utilize cell-culture-based production paths, which are often prone to failure.
• The therapeutics production segment is expected to expand at a significant CAGR of 2.65% from 2024 to 2030, due to the increasing prevalence of various chronic and infectious diseases.
• The biopharmaceutical and pharmaceutical companies segment dominated the market with the highest revenue share in 2023, due to the high commercial success of biopharmaceuticals and rapid growth in demand for therapeutics.
• Moreover, the biopharmaceutical and pharmaceutical segment is also expected to expand at a rapid pace during 2024-2030, owing to the increasing approvals of mRNA-based vaccines.
• North America dominated the global industry in 2023 and accounted for the largest share of more than 36.77% of the overall revenue in 2023, and is expected to grow at the highest CAGR over the forecast period.
• The mRNA synthesis raw materials market in the U.S. is expected to grow over the forecast period. The rising research funding, presence of key players, and availability of healthcare infrastructure are expected to contribute to the high revenue share.
• The mRNA synthesis raw materials market in Europe is growing due to a strong presence of well-established and emerging product manufacturers and continuous organic & inorganic growth strategies being adopted by them.
• The mRNA synthesis raw materials market in Asia Pacific held a significant share in 2023. With the rising healthcare spending and investments in the region, many raw material manufacturers are shifting to Asia Pacific countries which is contributing to the growing demand of the market.
• The mRNA synthesis raw materials market in the Middle East & Africa is expected to grow exponentially over the forecast period. MEA region is witnessing a significant growth due to improved infrastructure and policies laid down by regulatory bodies.

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mRNA Synthesis Raw Materials Market Segmentation

Grand View Research has segmented the global mRNA synthesis raw materials market on the basis of type, application, end-use, and region:

mRNA Synthesis Raw Materials Type Outlook (Revenue, USD Million, 2018 - 2030)

• Capping Agents
• Nucleotides
• Plasmid DNA
• Enzymes
• Others

mRNA Synthesis Raw Materials Application Outlook (Revenue, USD Million, 2018 - 2030)

• Vaccine Production
• Therapeutics Production
• Others

mRNA Synthesis Raw Materials End-use Outlook (Revenue, USD Million, 2018 - 2030)

• Biopharmaceutical & Pharmaceutical Companies
• CROs & CMOs
• Academic & Research Institutes

mRNA Synthesis Raw Materials Regional Outlook (Revenue, USD Million, 2018 - 2030)

• North America
• Europe
• Asia Pacific
• Latin America
• Middle East and Africa (MEA)

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